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Proceedings Paper

Rapid intraoperative margin assessment by using multi-modal third-harmonic generation and three-photon fluorescence microscopy
Author(s): Chi-Kuang Sun; Chien-Ting Kao; Yi-Hua Liao M.D.; Ming-Liang Wei
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Paper Abstract

Slide-free imaging of hematoxylin-eosin-stained whole mount tissues is demonstrated using multi-modal third harmonic generation and three photon fluorescence microscopy. As a result, the demonstrated microscopy shows promise for rapid margin assessment during surgery without compromising the contrast and features of conventional H&E histology.

Paper Details

Date Published: 19 July 2019
PDF: 3 pages
Proc. SPIE 11073, Clinical and Preclinical Optical Diagnostics II, 110730X (19 July 2019); doi: 10.1117/12.2525658
Show Author Affiliations
Chi-Kuang Sun, National Taiwan Univ. (Taiwan)
Chien-Ting Kao, National Taiwan Univ. (Taiwan)
Yi-Hua Liao M.D., National Taiwan Univ. (Taiwan)
Ming-Liang Wei, National Taiwan Univ. (Taiwan)

Published in SPIE Proceedings Vol. 11073:
Clinical and Preclinical Optical Diagnostics II
J. Quincy Brown; Ton G. van Leeuwen, Editor(s)

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