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Proceedings Paper

5-ALA induces the distribution of endogenous PpIX fluorescence in cervical lesions
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Paper Abstract

Objective: To investigate the distribution of ALA in Cervical lesion tissue by tissue frozen section and fluorescence microscopy. Methods: 20% of 5-ALA were topically applied to the cervix.Biopsies were taken from the lesions for histology examination, Fluorescence microscopy was performed methods in these frozen section of cervical tissue to observe the distribution of ALA and the result was analyzed semi-quantitatively. Results: The maximal Protoporphyrin IX (PpIX) fluorescence was observed in the most serious tissue with cervical lesions .fluorescence photometry corroborated these results. Conclusion: ALA is selectively accumulated in cervical lesions, and the more severe the lesion, the easier it is to accumulate.

Paper Details

Date Published: 7 August 2019
PDF: 2 pages
Proc. SPIE 11070, 17th International Photodynamic Association World Congress, 1107073 (7 August 2019); doi: 10.1117/12.2525359
Show Author Affiliations
XiaoLi Lu, Henan Provincial People's Hospital of Henan Univ. (China)
GuangZhi Liu, Henan Provincial People's Hospital (China)
People's Hospital of Zhengzhou Univ. (China)
LiYun Yang, Henan Provincial People's Hospital (China)
GuiQin Chen, Henan Provincial People's Hospital (China)
LeNan Cheng, Henan Provincial People's Hospital of Henan Univ. (China)
Bing Mao, Henan Provincial People's Hospital (China)
ZiYi Zhao, Jilin Univ. (China)
QiuYun Yang, Henan Provincial People's Hospital of Henan Univ. (China)


Published in SPIE Proceedings Vol. 11070:
17th International Photodynamic Association World Congress
Tayyaba Hasan, Editor(s)

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