A borderline reconstruction algorithm of optical structure disturbances of biomedical objects is described. The key features of it: (I) determination of the coordinates of the centers and effective size of each absorbing and scattering inhomogeneity in an investigated biological tissue, (II) refinement of the convex and concave parts of the boundary of each spherical inhomogeneity which is followed by smoothing the resulting structural image. The refinement of the parts of the boundary of a spherical inhomogeneity was made by adding or subtracting additional spheres. Centers of additional spheres were determined stochastically in the neighborhood of the boundary of the spherical inhomogeneity. Radii of additional spheres were calculated as one quarter of the length of the distance from the center of the additional sphere to the center of the spherical inhomogeneity.

Date Published: 3 June 2019
PDF: 8 pages
Proc. SPIE 11065, Saratov Fall Meeting 2018: Optical and Nano-Technologies for Biology and Medicine, 110650Y (3 June 2019); doi: 10.1117/12.2523238

Published in SPIE Proceedings Vol. 11065:
Saratov Fall Meeting 2018: Optical and Nano-Technologies for Biology and Medicine
Elina A. Genina; Valery V. Tuchin, Editor(s)