Share Email Print
cover

Proceedings Paper

Comparison of elastic properties of tissue samples in various pathological states using optical coherence elastography
Author(s): Ekaterina V. Gubarkova; Alexander A. Sovetsky; Vladimir Yu. Zaitsev; Lev A. Matveev; Alexander L. Matveyev ; Dmitry A. Vorontsov; Lydia B. Timofeeva; Elena B. Kiseleva; Alexey Yu. Vorontsov; Irina A. Kuznetsova; Natalia D. Gladkova
Format Member Price Non-Member Price
PDF $17.00 $21.00

Paper Abstract

Elastic properties of soft biological tissues may reflect their functional state and be a sensitive indicator of important pathological processes occurring in them. Using compressional optical coherent elastography (OCE) we revealed significant differences not only in the value of the Young modulus, but also in the character of elastic responses of biological tissues in different pathological states (including such key states as inflammatory, oncological and degenerative processes) in ex vivo human tissues. Here, we demonstrate a bright example of such qualitatively and quantitatively different trends: unlike breast cancer characterized by strongly elevated (in comparison with norm) stiffness that pronouncedly increases with compression, stiffness of pelvic organ prolapse is strongly decreased and weakly varies with compression.

Paper Details

Date Published: 3 June 2019
PDF: 5 pages
Proc. SPIE 11065, Saratov Fall Meeting 2018: Optical and Nano-Technologies for Biology and Medicine, 110650D (3 June 2019); doi: 10.1117/12.2521529
Show Author Affiliations
Ekaterina V. Gubarkova, Privolzhsky Research Medical Univ. (Russian Federation)
Alexander A. Sovetsky, Institute of Applied Physics (Russian Federation)
Vladimir Yu. Zaitsev, Institute of Applied Physics (Russian Federation)
Lev A. Matveev, Institute of Applied Physics (Russian Federation)
Alexander L. Matveyev , Institute of Applied Physics (Russian Federation)
Dmitry A. Vorontsov, Nizhny Novgorod Regional Oncologic Hospital (Russian Federation)
Lydia B. Timofeeva, Privolzhsky Research Medical Univ. (Russian Federation)
Elena B. Kiseleva, Privolzhsky Research Medical Univ. (Russian Federation)
Alexey Yu. Vorontsov, Nizhny Novgorod Regional Oncologic Hospital (Russian Federation)
Irina A. Kuznetsova, Nizhny Novgorod Regional Clinical Hospital (Russian Federation)
Natalia D. Gladkova, Privolzhsky Research Medical Univ. (Russian Federation)


Published in SPIE Proceedings Vol. 11065:
Saratov Fall Meeting 2018: Optical and Nano-Technologies for Biology and Medicine
Elina A. Genina; Valery V. Tuchin, Editor(s)

© SPIE. Terms of Use
Back to Top
PREMIUM CONTENT
Sign in to read the full article
Create a free SPIE account to get access to
premium articles and original research
Forgot your username?
close_icon_gray