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Proceedings Paper

Diagnosis of lymph node metastasis in non-small-cell lung cancer (NSCLC) patient on F-18-FDG PET/CT
Author(s): Tsu-Chi Cheng; Nan-Tsing Chiu; Ting-Yu Su; Yi-Fei He; Wei-Tse Yang; Yu-Hua Fang
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Paper Abstract

Lung Cancer is a leading cause of death worldwide, and about 85% of lung cancer is non-small cell lung cancer (NSCLC). The staging of lymph nodes in NSCLC patients is extremely important because respective stages require different treatments. FDG-PET/CT is a gold standard for lymph node metastasis staging of NSCLC. However, the results of discriminating lymph node staging on 18F-2-fluoro-2-deoxy-d-glucose (FDG) positron emission tomography (PET) / computed tomography (CT) still needs improvement. In addition to the traditional image parameters of FDG-PET/CT such as standardized uptake value (SUV), there are many other parameters available from FDG-PET/CT images, for example, the lymphatic drainage pathway. Other than this, texture analysis which distinguishes subtle difference can also be a way to define lymph node staging. For the purpose of a better accuracy on lymph node metastasis diagnosis on NSCLC patient in FDG-PET/CT, this research developed a computer-aided diagnosis (CAD) system to improve the diagnostic efficiency, which achieved 88.056% accuracy.

Paper Details

Date Published: 27 March 2019
PDF: 4 pages
Proc. SPIE 11050, International Forum on Medical Imaging in Asia 2019, 110500Z (27 March 2019); doi: 10.1117/12.2521510
Show Author Affiliations
Tsu-Chi Cheng, National Cheng Kung Univ. (Taiwan)
Nan-Tsing Chiu, National Cheng Kung Univ. Hospital (Taiwan)
Ting-Yu Su, National Cheng Kung Univ. (Taiwan)
Yi-Fei He, National Cheng Kung Univ. (Taiwan)
Wei-Tse Yang, National Cheng Kung Univ. (Taiwan)
Yu-Hua Fang, National Cheng Kung Univ. (Taiwan)

Published in SPIE Proceedings Vol. 11050:
International Forum on Medical Imaging in Asia 2019
Feng Lin; Hiroshi Fujita; Jong Hyo Kim, Editor(s)

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