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Proceedings Paper

Perspectives and advances in optical elastography
Author(s): Jannick P. Rolland; Fernando Zvietcovich; Gary R. Ge; Kevin J. Parker
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Paper Abstract

In medicine, both pathological (e.g. cirrhosis) and non-pathological states (e.g. aging) can be characterized by changes in the mechanical properties of biological tissue. The use of optical techniques to measure and map the elastic properties of soft tissue, known as optical elastography, is an emergent field with applications in various clinical disciplines, including ophthalmology and dermatology. In this paper, a brief overview of optical elastography will be provided with a short taxonomy. Categories include appropriate types of tissue models (semi-infinite, single thin layer, composite stacks), clinical tasks (classification or estimation), and excitation modes (transient, continuous, quasi-static, or molecular shift). We will then discuss examples of current advances, including optical coherence elastography using reverberant shear wave fields and Brillouin microscopy. The examples will demonstrate how current and future techniques may address clinical needs. Advantages and disadvantages of these techniques will be presented, augmenting the framework of the categorization system. With emerging applications, the taxonomy may be expanded providing a roadmap to future techniques.

Paper Details

Date Published: 21 February 2019
PDF: 12 pages
Proc. SPIE 10880, Optical Elastography and Tissue Biomechanics VI, 108800G (21 February 2019); doi: 10.1117/12.2515946
Show Author Affiliations
Jannick P. Rolland, The Institute of Optics, Univ. of Rochester (United States)
Fernando Zvietcovich, Univ. of Rochester (United States)
Gary R. Ge, The Institute of Optics, Univ. of Rochester (United States)
Kevin J. Parker, Univ. of Rochester (United States)

Published in SPIE Proceedings Vol. 10880:
Optical Elastography and Tissue Biomechanics VI
Kirill V. Larin; Giuliano Scarcelli, Editor(s)

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