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Proceedings Paper

High-throughput image-activated cell sorting with intelligence (Conference Presentation)

Paper Abstract

In this talk, I introduce high-throughput intelligence-powered image-activated cell sorting or an “imaging” version of fluorescence-activated cell sorting [Cell 175, 1 (2018)] that realizes real-time image-based intelligent cell sorting at an unprecedented rate of ~100 events per second. This technology integrates high-speed cell microscopy, focusing, and sorting methods on rapid hybrid software-hardware data-management infrastructure, enabling real-time automated operation for data acquisition, data processing, decision-making, and actuation. I present two unique applications in microbiology and hematology enabled by the technology and discuss how technology enables machine-based scientific discovery in diverse biological and medical sciences.

Paper Details

Date Published: 4 March 2019
Proc. SPIE 10889, High-Speed Biomedical Imaging and Spectroscopy IV, 108890R (4 March 2019); doi: 10.1117/12.2515293
Show Author Affiliations
Nao Nitta, The Univ. of Tokyo (Japan)
Japan Science and Technology Agency (Japan)
CYBO, Inc. (Japan)
Takeaki Sugimura, The Univ. of Tokyo (Japan)
Japan Science and Technology Agency (Japan)
Yoichiroh Hosokawa, Nara Institute of Science and Technology (Japan)
Sotaro Uemura, The Univ. of Tokyo (Japan)
Yasuyuki Ozeki, The Univ. of Tokyo (Japan)
Keisuke Goda, The Univ. of Tokyo (Japan)
Japan Science and Technology Agency (Japan)
Univ. of California, Los Angeles (United States)

Published in SPIE Proceedings Vol. 10889:
High-Speed Biomedical Imaging and Spectroscopy IV
Kevin K. Tsia; Keisuke Goda, Editor(s)

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