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Proceedings Paper

Long-range surface plasmon waveguide biosensors for disease detection
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Paper Abstract

We review long-range surface plasmon-polariton waveguide biosensors and their application to disease detection in complex fluids. The biosensors are constructed from metal stripe waveguides cladded in Cytop with etched microfluidic channels to expose the stripe surface to the sensing fluid. Application of waveguide biosensors to the detection of leukemia in patient blood serum and dengue infection in patient blood plasma is reviewed. In addition, a novel bioassay for HIV detection in complex fluids is proposed and preliminary results are demonstrated. The biosensors are compact and mass manufacturable using semiconductor fabrication tools and processes.

Paper Details

Date Published: 7 March 2019
PDF: 11 pages
Proc. SPIE 10895, Frontiers in Biological Detection: From Nanosensors to Systems XI, 108950T (7 March 2019); doi: 10.1117/12.2513773
Show Author Affiliations
Oleksiy Krupin, Univ. of Ottawa (Canada)
Wei Ru Wong, Univ. of Malaya (Malaysia)
Pierre Berini, Univ. of Ottawa (Canada)

Published in SPIE Proceedings Vol. 10895:
Frontiers in Biological Detection: From Nanosensors to Systems XI
Amos Danielli; Benjamin L. Miller; Sharon M. Weiss, Editor(s)

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