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Proceedings Paper

Molecular modeling of multilayer cellular and tissue engineering structures based on a wireframe of carbon nanotubes and protein matrix for restoring the tissues of the heart and blood vessels
Author(s): O. E. Glukhova; D. S. Shmygin
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Paper Abstract

This work is devoted to the development of a methodology for modeling a multilayer and multi-component biostructure from individual layers for restoration of tissues of heart and blood vessels. Structural elements of considered complex bioconstruction are alternating layers of carbon nanotubes and albumin, carbon nanotubes and collagen, and also carbon nanotubes and chitosan. The atomistic and coarse-grained models of individual layers of structures are constructed, and its assembly is carried out in the presence of water using molecular dynamics. The binding energies of the individual layers with each other are calculated to create a subsequent multi-layer elastic structure.

Paper Details

Date Published: 7 March 2019
PDF: 5 pages
Proc. SPIE 10893, Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications XI, 108930X (7 March 2019); doi: 10.1117/12.2511084
Show Author Affiliations
O. E. Glukhova, Saratov State Univ. (Russian Federation)
I.M. Sechenov First Moscow State Medical Univ. (Russian Federation)
D. S. Shmygin, Saratov State Univ. (Russian Federation)


Published in SPIE Proceedings Vol. 10893:
Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications XI
Samuel Achilefu; Ramesh Raghavachari, Editor(s)

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