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Proceedings Paper

Uptake of a fluorescence imaging agent in an orthotopic glioblastoma using fluorescence molecular tomography
Author(s): Negar Sadeghipour; Boyu Meng; Margaret R. Folaron; Rendall R. Strawbridge; Kimberley S. Samkoe; Kenneth M. Tichauer; Scott C. Davis
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Paper Abstract

We reported the uptake value of a near-infrared imaging agent in an orthotopic glioma mouse models. The imaging agent was IRDy680®. The mice were injected with a trace amount of this imaging agent and imaged on a magnetic resonance imaging device that is coupled with a fluorescence imaging tomography system. By applying a reconstruction method, at each time point, we got a single value for the uptake of this imaging agent in the tumor region. The mean of the uptake values in the mice is reported here.

Paper Details

Date Published: 7 March 2019
PDF: 5 pages
Proc. SPIE 10862, Molecular-Guided Surgery: Molecules, Devices, and Applications V, 108620J (7 March 2019); doi: 10.1117/12.2510904
Show Author Affiliations
Negar Sadeghipour, Illinois Institute of Technology (United States)
Boyu Meng, Dartmouth College (United States)
Margaret R. Folaron, Dartmouth College (United States)
Rendall R. Strawbridge, Dartmouth College (United States)
Kimberley S. Samkoe, Dartmouth College (United States)
Geisel School of Medicine, Dartmouth College (United States)
Kenneth M. Tichauer, Illinois Institute of Technology (United States)
Scott C. Davis, Dartmouth College (United States)


Published in SPIE Proceedings Vol. 10862:
Molecular-Guided Surgery: Molecules, Devices, and Applications V
Brian W. Pogue; Sylvain Gioux, Editor(s)

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