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Proceedings Paper

Sensitivity analysis of a multibranched light guide for real time hyperspectral imaging systems
Author(s): Craig M. Browning; Samuel Mayes; Joshua Deal; Arslan Arshad; Samantha Gunn Mayes; Marina Parker; Thomas C. Rich; Silas J. Leavesley
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Paper Abstract

Hyperspectral imaging (HSI) is a spectroscopic technique which captures images at a high contrast over a wide range of wavelengths to show pixel specific composition. Traditional uses of HSI include: satellite imagery, food distribution quality control and digital archaeological reconstruction. Our lab has focused on developing applications of HSI fluorescence imaging systems to study molecule-specific detection for rapid cell signaling events or real-time endoscopic screening. Previously, we have developed a prototype spectral light source, using our modified imaging technique, excitationscanning hyperspectral imaging (HIFEX), coupled to a commercial colonoscope for feasibility testing. The 16 wavelength LED array was combined, using a multi-branched solid light guide, to couple to the scope’s optical input. The prototype acquired a spectral scan at near video-rate speeds (~8 fps). The prototype could operate at very rapid wavelength switch speeds, limited to the on/off rates of the LEDs (~10 μs), but imaging speed was limited due to optical transmission losses (~98%) through the solid light guide. Here we present a continuation of our previous work in performing an in-depth analysis of the solid light guide to optimize the optical intensity throughput. The parameters evaluated include: LED intensity input, geometry (branch curvature and combination) and light propagation using outer claddings. Simulations were conducted using a Monte Carlo ray tracing software (TracePro). Results show that transmission within the branched light guide may be optimized through LED focusing lenses, bend radii and smooth tangential branch merges. Future work will test a new fabricated light guide from the optimized model framework.

Paper Details

Date Published: 27 February 2019
PDF: 9 pages
Proc. SPIE 10871, Multimodal Biomedical Imaging XIV, 1087107 (27 February 2019); doi: 10.1117/12.2510506
Show Author Affiliations
Craig M. Browning, Univ. of South Alabama (United States)
Samuel Mayes, Univ. of South Alabama (United States)
Joshua Deal, Univ. of South Alabama (United States)
Arslan Arshad, Univ. of South Alabama (United States)
Samantha Gunn Mayes, Univ. of South Alabama (United States)
Marina Parker, Univ. of South Alabama (United States)
Thomas C. Rich, Univ. of South Alabama (United States)
Silas J. Leavesley, Univ. of South Alabama (United States)


Published in SPIE Proceedings Vol. 10871:
Multimodal Biomedical Imaging XIV
Fred S. Azar; Xavier Intes; Qianqian Fang, Editor(s)

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