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Proceedings Paper

Quantifying lens elastic properties with optical coherence elastography as a function of intraocular pressure
Author(s): Chen Wu; Hongqiu Zhang; Manmohan Singh; Salavat R. Aglyamov; Kirill V. Larin
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Paper Abstract

Normal intraocular pressure (IOP) is crucial for proper maintaining of eye-globe geometry, ocular tissue health, and visual acuity. An elevated IOP is associated with diseases such as glaucoma and uveitis. While the effects of an elevated IOP on the delicate tissues of the optic nerve head and retina are well-studied, the changes in lenticular biomechanical properties as a function of IOP are not as clear. Moreover, changes in lenticular biomechanical properties have been implicated in conditions and diseases such as presbyopia and cataract. However, measuring the biomechanical properties of the lens as it sits inside the eye-globe is a challenge, but it is necessary to correctly understand the interplay between lenticular biomechanical properties and IOP. In this work, we utilized optical coherence elastography (OCE) to measure the biomechanical properties of the porcine lens in situ.

Paper Details

Date Published: 21 February 2019
PDF: 5 pages
Proc. SPIE 10880, Optical Elastography and Tissue Biomechanics VI, 108801P (21 February 2019); doi: 10.1117/12.2510225
Show Author Affiliations
Chen Wu, Univ. of Houston (United States)
Hongqiu Zhang, Univ. of Houston (United States)
Manmohan Singh, Univ. of Houston (United States)
Salavat R. Aglyamov, Univ. of Houston (United States)
Univ. of Texas at Austin (United States)
Kirill V. Larin, Univ. of Houston (United States)
Tomsk State Univ. (Russian Federation)
Baylor College of Medicine (United States)

Published in SPIE Proceedings Vol. 10880:
Optical Elastography and Tissue Biomechanics VI
Kirill V. Larin; Giuliano Scarcelli, Editor(s)

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