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Proceedings Paper

Ultracompact high resolution photoacoustic microscopy of hemorrhagic shock
Author(s): Qian Chen; Lei Xi
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Paper Abstract

Hemorrhagic shock, as an important clinical issue, is regarding as a critical disease with a high mortality rate. Unfortunately, existing clinical technologies are inaccessible to assess the hemorrhagic shock via hemodynamics in microcirculation. Here, we proposed an ultracompact photoacoustic microscope to assess hemorrhagic shock by using a rat model. In animal study, hemodynamic features of the microvascular network including concentration of total hemoglobin (CHbT) and small vascular density (SVD) were derived to assess the microvascular hemodynamics of different organs, assessing the hemorrhagic shock via microcirculation. On the other hand, in vivo oral imaging of healthy volunteers also indicates the translational possibility of this technique for clinical evaluation of hemorrhagic shock.

Paper Details

Date Published: 27 February 2019
PDF: 6 pages
Proc. SPIE 10878, Photons Plus Ultrasound: Imaging and Sensing 2019, 108782Z (27 February 2019); doi: 10.1117/12.2506218
Show Author Affiliations
Qian Chen, Southern Univ. of Science and Technology of China (China)
Lei Xi, Southern Univ. of Science and Technology of China (China)


Published in SPIE Proceedings Vol. 10878:
Photons Plus Ultrasound: Imaging and Sensing 2019
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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