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Proceedings Paper

The influence of bilirubin and creatinine on the refractive index of whole blood in terahertz frequency range: a qualitative analysis
Author(s): Tianmiao Zhang; Petr Demchenko; Mikhail K. Khodzitsky; Yulia Kononova; Alina Babenko M.D.; Elena Grineva M.D.
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Paper Abstract

The glucose level of blood can be obtained by terahertz time-domain spectroscopy using refractive index measurement method. The detected refractive indices vary from person to person since the impact of bilirubin and creatinine wasn’t considered. 14 human blood samples were tested using terahertz time-domain spectroscopy. The experiment results show that under the certain concentration of glucose, the refractive index of blood decreases with the increase of bilirubin and creatinine concentration, and thus the concentration of other blood components may also influence on the refractive index of blood. The feasibility of using terahertz time-domain spectroscopy to determine the level of glucose, bilirubin and creatinine qualitatively and quantitatively is provided.

Paper Details

Date Published: 23 October 2018
PDF: 7 pages
Proc. SPIE 10820, Optics in Health Care and Biomedical Optics VIII, 108200P (23 October 2018); doi: 10.1117/12.2500855
Show Author Affiliations
Tianmiao Zhang, ITMO Univ. (Russian Federation)
Petr Demchenko, ITMO Univ. (Russian Federation)
Mikhail K. Khodzitsky, ITMO Univ. (Russian Federation)
Yulia Kononova, Almazov National Medical Research Ctr. (Russian Federation)
Alina Babenko M.D., Almazov National Medical Research Ctr. (Russian Federation)
Elena Grineva M.D., Almazov National Medical Research Ctr. (Russian Federation)


Published in SPIE Proceedings Vol. 10820:
Optics in Health Care and Biomedical Optics VIII
Qingming Luo; Xingde Li; Ying Gu; Yuguo Tang, Editor(s)

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