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Proceedings Paper

Cellular phase observations and measurements on red blood cells affected by lithium and lead ions with quantitative interferometric microscopy
Author(s): Qi Wei; Zhilong Jiang; Yan Kong; Keding Yan; Liang Xue; Cheng Liu; Shouyu Wang
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Paper Abstract

As an important marker in disease diagnosis, red blood cell morphology measurement is necessary in biological and medical fields. However, traditional setups as microscopes and cytometers cannot provide enough quantitative information in morphology detections. In order to capture tiny variations of red blood cells affected by metal ions in external environment, quantitative interferometric microscopy is applied: combining with phase retrieval and cell recognition, cellular phases as well as additional quantitative cellular parameters can be acquired automatically and accurately. The research proves that quantitative interferometric microscopy can be potentially applied in cellular observations and measurements for both biological and medical applications.

Paper Details

Date Published: 23 October 2018
PDF: 12 pages
Proc. SPIE 10820, Optics in Health Care and Biomedical Optics VIII, 108201J (23 October 2018); doi: 10.1117/12.2500573
Show Author Affiliations
Qi Wei, Jiangnan Univ. (China)
Zhilong Jiang, Jiangnan Univ. (China)
Yan Kong, Jiangnan Univ. (China)
Keding Yan, Xi’an Technological Univ. (China)
Liang Xue, Shanghai Univ. of Electric Power (China)
Cheng Liu, Jiangnan Univ. (China)
Shouyu Wang, Jiangnan Univ. (China)

Published in SPIE Proceedings Vol. 10820:
Optics in Health Care and Biomedical Optics VIII
Qingming Luo; Xingde Li; Ying Gu; Yuguo Tang, Editor(s)

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