Opto-Thermal Transient Emission Radiometry has been shown to be able to measure stratum corneum hydration in-vivo. We now present a study that shows how the technique can be extended to give information about the distribution of water within the stratum corneum. This depth profile measurement capability is based on a new theoretical expression for the opto- thermal signal that takes a gradient of water concentration explicitly into account. The technique is illustrated with measurements on untreated skin and skin treated with petroleum jelly and DMSO.

Date Published: 7 May 1996
PDF: 11 pages
Proc. SPIE 2681, Laser-Tissue Interaction VII, (7 May 1996); doi: 10.1117/12.239588

Published in SPIE Proceedings Vol. 2681:
Laser-Tissue Interaction VII
Steven L. Jacques, Editor(s)