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Proceedings Paper

Application of the new methodology of quantitative evaluation of morphofunctional changes in RBCs induced by low-dose irradiation of donors
Author(s): Alexander V. Priezzhev; Andrey A. Dergachev; Victor F. Kopylov; Alexander V. Zhukotsky; Elena B. Lomakina; Emmanuil M. Kogan
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Paper Abstract

We are reporting on the results obtained in the development of our previous paper. We have implemented the previously described unified approach of particle image velocimetry and computer morphodensitometry trying to find correlation between morphofunctional and dynamic parameters of red blood cells of human donors who had undergone low-doze ionizing irradiation conventionally used in radiology. Specifically we examined the suspension of RBCs obtained from children who had accidentally or therapeutically undergone irradiation with different doses (0.03-0.04 Gy), and compared them to controls. Our experiments have shown the existence of correlation between the rheological and morphometric indexes obtained with the help of the computer image processing system Diamorph.

Paper Details

Date Published: 10 May 1996
PDF: 5 pages
Proc. SPIE 2678, Optical Diagnostics of Living Cells and Biofluids, (10 May 1996); doi: 10.1117/12.239521
Show Author Affiliations
Alexander V. Priezzhev, M.V. Lomonosov Moscow State Univ. (Russia)
Andrey A. Dergachev, M.V. Lomonosov Moscow State Univ. (Russia)
Victor F. Kopylov, DiaMorph Ltd. (Russia)
Alexander V. Zhukotsky, DiaMorph Ltd. (Russia)
Elena B. Lomakina, DiaMorph Ltd. (Russia)
Emmanuil M. Kogan, DiaMorph Ltd. (Russia)

Published in SPIE Proceedings Vol. 2678:
Optical Diagnostics of Living Cells and Biofluids
Daniel L. Farkas; Robert C. Leif; Alexander V. Priezzhev; Toshimitsu Asakura; Bruce J. Tromberg, Editor(s)

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