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Proceedings Paper

spectral fluorescence analysis and photodynamic activity of some phthalocyanines in experiments in vivo
Author(s): V. E. Normansky M.D.; Natalia N. Zharkova; M. V. Baryshev; E. A. Lukinetc; O. L. Kaliya; Victor B. Loschenov
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Paper Abstract

A great variety of new chemical compounds, potential photosensitizers, require testing their photodynamic activity ( PDA ) and tumor localizing capacity. Comparative analysis of phthalocyanines according to qiven criteria seems to be urgent, phthalocyanines being most prospective photosensitizers for photodynamic therapy ( PDT ) of malignant tumors ( 1, 2 ). The absence of scientificly based correlations between the compound chemical structure and its photodynamic activity puts forward the task of initial screening estimation of photosensitizing and tumor localizing properties of chemical compounds.

Paper Details

Date Published: 1 September 1990
PDF: 5 pages
Proc. SPIE 1353, First International Conference on Lasers and Medicine, (1 September 1990); doi: 10.1117/12.23766
Show Author Affiliations
V. E. Normansky M.D., National Ctr. for Laser Surgery of the USSR (Russia)
Natalia N. Zharkova, Institute of Optical-Physical (Russia)
M. V. Baryshev, Institute of Optical-Physical (Russia)
E. A. Lukinetc, Ctr. of Medical Lasers and Optical Diagnostics (Russia)
O. L. Kaliya, Ctr. of Medical Lasers and Optical Diagnostics (Russia)
Victor B. Loschenov, First Moscow Medical Institute (Russia)

Published in SPIE Proceedings Vol. 1353:
First International Conference on Lasers and Medicine
Vitali I. Konov; Gerhard J. Mueller; Alexander M. Prokhorov, Editor(s)

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