The aim of this paper is to show relationship first, between light parameters and biostimulation (metabolism regulation effect), and second, between physiological conditions of cells at the moment of irradiation and stimulation effects magnitude. These studies have been performed on cellular level, and as a model, a culture of procaryotic cells Escherichia coil WP2 was used. As a criterion for the division rate of E. coil WP2 cells was measured. There is no grounds to believe the existence of a single universal biostimula tion mechanism active on molecular, cellular, and organism levels. On the other hand, undoubtedly there are many connections between mechanisms of light stimulation on different levels. For example, as concerning light stimulation on organism level (i.e., low-power laser therapy), there exist dependences of therapeutic effects on parameters of light (fluence, intensity) (see reviews: Karu, 1990 a, b). As far as mechanism of biostimulation is concerned, we will show in this paper that the stimulation effects are connected with certain chromophores (primary photoacceptors) in a cell.

Date Published: 1 September 1990
PDF: 11 pages
Proc. SPIE 1353, First International Conference on Lasers and Medicine, (1 September 1990); doi: 10.1117/12.23743

Published in SPIE Proceedings Vol. 1353:
First International Conference on Lasers and Medicine
Vitali I. Konov; Gerhard J. Mueller; Alexander M. Prokhorov, Editor(s)