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Proceedings Paper

Terahertz spectroscopy of immersion optical clearing agents: DMSO, PG, EG, PEG
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Paper Abstract

Application of terahertz (THz) spectroscopy for biological tissues is strongly limited by the extremely low penetration depth due to THz absorption by tissue water. One of the possible solution of such problem is the usage of THz wave penetration-enhancing agents (PEA) for optical clearing of tissues. In the present paper, the transmission-mode THz spectroscopy of a set of PEAs (polyethylene glycol with different molecular weight, propylene glycol, ethylene glycol, and dimethyl sulfoxide) was performed in order to reconstruct their dielectric properties and compare them with that of water. The obtained results emphasize the feasibility of using PEG to enhance the depth of THz wave penetration into tissues.

Paper Details

Date Published: 5 October 2018
PDF: 7 pages
Proc. SPIE 10800, Millimetre Wave and Terahertz Sensors and Technology XI, 108000F (5 October 2018); doi: 10.1117/12.2324473
Show Author Affiliations
Guzel R. Musina, Prokhorov General Physics Institute (Russian Federation)
Bauman Moscow State Technical Univ. (Russian Federation)
Irina N. Dolganova, Bauman Moscow State Technical Univ. (Russian Federation)
Institute of Solid State Physics (Russian Federation)
Sechenov First Moscow State Medical Univ. (Russian Federation)
Kirill M. Malakhov, Prokhorov General Physics Institute (Russian Federation)
Bauman Moscow State Technical Univ. (Russian Federation)
Arseniy A. Gavdush, Prokhorov General Physics Institute (Russian Federation)
Bauman Moscow State Technical Univ. (Russian Federation)
Nikita V. Chernomyrdin, Prokhorov General Physics Institute (Russian Federation)
Bauman Moscow State Technical Univ. (Russian Federation)
Institute of Solid State Physics (Russian Federation)
Daria K. Tuchina, Prokhorov General Physics Institute (Russian Federation)
Saratov State Univ. (Russian Federation)
Tomsk State Univ. (Russian Federation)
Gennady A. Komandin, Prokhorov General Physics Institute (Russian Federation)
Sergey V. Chuchupal, Prokhorov General Physics Institute (Russian Federation)
Olga P. Cherkasova, Institute of Laser Physics (Russian Federation)
Tomsk State Univ. (Russian Federation)
Kirill I. Zaytsev, Prokhorov General Physics Institute (Russian Federation)
Bauman Moscow State Technical Univ. (Russian Federation)
Sechenov First Moscow State Medical Univ. (Russian Federation)
Valery V. Tuchin, Saratov State Univ. (Russian Federation)
Institute of Precision Mechanics and Control (Russian Federation)
Tomsk State Univ. (Russian Federation)


Published in SPIE Proceedings Vol. 10800:
Millimetre Wave and Terahertz Sensors and Technology XI
Neil A. Salmon; Frank Gumbmann, Editor(s)

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