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Proceedings Paper

Independent pathway for inclusion complexes of porphyrinoid drugs in tumors: the separation from the lipoprotein pathway in plasma
Author(s): Joerg G. Moser; Anja Ruebner-Heuermann; Andrea Weitemeyer; Ulrike Michelsen; Dieter Woehrle; Angelika C. Rueck; Wolfgang S. L. Strauss; Dieter Kirsch; Sonja Andrees; Chrs. Schroers
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Paper Abstract

Phthalocyanines and m-TPPs were substituted with two or three t-butyl phenyl anchor groups to build up inclusion complexes with dimeric (beta) -cyclodextrins. These complexes proved to be stable enough to hinder complexation of the porphyrinoids with plasma lipoproteins and, so, offer an independent pathway to transfer porphyrinoids to photosensitize tumor tissue.

Paper Details

Date Published: 31 January 1996
PDF: 8 pages
Proc. SPIE 2625, Photochemotherapy: Photodynamic Therapy and Other Modalities, (31 January 1996); doi: 10.1117/12.230980
Show Author Affiliations
Joerg G. Moser, Heinrich-Heine-Univ. (Germany)
Anja Ruebner-Heuermann, Heinrich-Heine-Univ. (Germany)
Andrea Weitemeyer, Univ. Bremen (Germany)
Ulrike Michelsen, Univ. Bremen (Germany)
Dieter Woehrle, Univ. Bremen (Germany)
Angelika C. Rueck, Institut fuer Lasertechnologien in der Medizin und Messtechnik an der Univ. Ulm (Germany)
Wolfgang S. L. Strauss, Institut fuer Lasertechnologien in der Medizin und Messtechnik an der Univ. Ulm (Germany)
Dieter Kirsch, Heinrich-Heine-Univ. (Germany)
Sonja Andrees, Heinrich-Heine-Univ. (Germany)
Chrs. Schroers, Heinrich-Heine-Univ. (Germany)


Published in SPIE Proceedings Vol. 2625:
Photochemotherapy: Photodynamic Therapy and Other Modalities
Benjamin Ehrenberg; Giulio Jori; Johan Moan, Editor(s)

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