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Proceedings Paper

Visualization of nanoconstructions with DNA-Aptamers for targeted molecules binding on the surface of screen-printed electrodes
Author(s): Ivan N. Lapin; Anastasiia V. Shabalina; Valery A. Svetlichyi; Olga S. Kolovskaya
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Paper Abstract

Nanoconstructions of gold nanoparticles (NPs) obtained via pulsed laser ablation in liquid with DNA-aptamer specific to protein tumor marker were visualized on the surface of screen-printed electrode using scanning electron microscopy (SEM) and confocal laser scanning microscopy (CLSM). AuNPs/aptamer nanoconstuctions distribution on the solid surface was studied. More uniform coverage of the carbon electrode surface with the nanoconstuctions was showed in comparison with DNA-aptamer alone on the golden electrode surface. Targeted binding of the tumor marker molecules with the AuNPs/DNA-aptamer nanoconstuctions was approved.

Paper Details

Date Published: 16 April 2018
PDF: 4 pages
Proc. SPIE 10614, International Conference on Atomic and Molecular Pulsed Lasers XIII, 106141R (16 April 2018); doi: 10.1117/12.2304745
Show Author Affiliations
Ivan N. Lapin, Tomsk State Univ. (Russian Federation)
Anastasiia V. Shabalina, Tomsk State Univ. (Russian Federation)
Valery A. Svetlichyi, Tomsk State Univ. (Russian Federation)
Olga S. Kolovskaya, Krasnoyarsk State Medical Univ. (Russian Federation)

Published in SPIE Proceedings Vol. 10614:
International Conference on Atomic and Molecular Pulsed Lasers XIII
Andrei M. Kabanov; Victor F. Tarasenko, Editor(s)

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