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Proceedings Paper

Computed aided system for separation and classification of the abnormal erythrocytes in human blood
Author(s): Michał Wąsowicz; Michał Grochowski; Marek Kulka; Agnieszka Mikołajczyk; Mateusz Ficek; Katarzyna Karpieńko; Maciej Cićkiewicz
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Paper Abstract

The human peripheral blood consists of cells (red cells, white cells, and platelets) suspended in plasma. In the following research the team assessed an influence of nanodiamond particles on blood elements over various periods of time. The material used in the study consisted of samples taken from ten healthy humans of various age, different blood types and both sexes. The markings were leaded by adding to the blood unmodified diamonds and oxidation modified. The blood was put under an impact of two diamond concentrations: 20μl and 100μl. The amount of abnormal cells increased with time. The percentage of echinocytes as a result of interaction with nanodiamonds in various time intervals for individual specimens was scarce. The impact of the two diamond types had no clinical importance on red blood cells. It is supposed that as a result of longlasting exposure a dehydratation of red cells takes place, because of the function of the cells. The analysis of an influence of nanodiamond particles on blood elements was supported by computer system designed for automatic counting and classification of the Red Blood Cells (RBC). The system utilizes advanced image processing methods for RBCs separation and counting and Eigenfaces method coupled with the neural networks for RBCs classification into normal and abnormal cells purposes.

Paper Details

Date Published: 7 December 2017
PDF: 7 pages
Proc. SPIE 10592, Biophotonics—Riga 2017, 105920A (7 December 2017); doi: 10.1117/12.2297218
Show Author Affiliations
Michał Wąsowicz, Warsaw Univ. of Life Sciences (Poland)
Praktyka Weterynaryjna (Poland)
Michał Grochowski, Gdańsk Univ. of Technology (Poland)
Marek Kulka, Warsaw Univ. of Life Sciences (Poland)
Agnieszka Mikołajczyk, Gdansk Univ. of Technology (Poland)
Mateusz Ficek, Gdansk Univ. of Technology (Poland)
Katarzyna Karpieńko, Gdansk Univ. of Technology (Poland)
Maciej Cićkiewicz, DentalMovies (Poland)

Published in SPIE Proceedings Vol. 10592:
Biophotonics—Riga 2017
Janis Spigulis, Editor(s)

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