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Proceedings Paper

Bare laser-synthesized Si nanoparticles as functional elements for chitosan nanofiber-based tissue engineering platforms
Author(s): Anton A. Popov; Ahmed Al-Kattan; Viraj P. Nirwan; Emilie Munnier; Gleb I. Tselikov; Yury V. Ryabchikov; Igor Chourpa; Amir Fahmi; A. V. Kabashin
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Paper Abstract

Methods of femtosecond laser ablation were used to fabricate bare (ligand-free) silicon (Si) nanoparticles in deionized water. The nanoparticles were round in shape, crystalline, free of any impurities, and water-dissolvable, while the dissolution rate depended on the concentration of oxygen defects in their composition. The nanoparticles were then eletrospun with chitosan to form nanoparticle decorated nanofibrous matrices. We found that the functionalization of nanofibers by the nanoparticles can affect the morphology and physico-chemical characteristics of resulting nanostructures. In particular, the presence of Si nanoparticles led to the reduction of fibers thickness, suggesting a potential improvement of fiber’s surface reactivity. We also observed the improvement of thermal stability of hybrid nanofibers. We believe that the incorporated Si nanoparticles can serve as functional elements to improve characteristics of chitosan-based matrices for cellular growth, as well as to enable novel imaging or therapeutic functionalities for tissue engineering applications.

Paper Details

Date Published: 23 February 2018
PDF: 8 pages
Proc. SPIE 10521, Synthesis and Photonics of Nanoscale Materials XV, 105210A (23 February 2018); doi: 10.1117/12.2295196
Show Author Affiliations
Anton A. Popov, Aix-Marseille Univ., CNRS, LP3 (France)
Ahmed Al-Kattan, Aix-Marseille Univ., CNRS, LP3 (France)
Viraj P. Nirwan, Rhine-Waal Univ. of Applied Sciences (Germany)
Emilie Munnier, Univ. Francois-Rabelais (France)
Gleb I. Tselikov, Aix-Marseille Univ., CNRS, LP3 (France)
Yury V. Ryabchikov, Aix-Marseille Univ., CNRS, LP3 (France)
Igor Chourpa, Univ. Francois-Rabelais (France)
Amir Fahmi, Rhine-Waal Univ. of Applied Sciences (Germany)
A. V. Kabashin, Aix-Marseille Univ., CNRS, LP3 (France)
National Research Nuclear Univ. MEPhI (Russian Federation)

Published in SPIE Proceedings Vol. 10521:
Synthesis and Photonics of Nanoscale Materials XV
Jan J. Dubowski; Andrei V. Kabashin; Linyou Cao; David B. Geohegan, Editor(s)

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