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Proceedings Paper

Automated quantification of cardiomyocytes beating profile with time-lapse digital holographic microscopy
Author(s): Inkyu Moon; Keyvan Jaferzadeh
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Paper Abstract

This paper overviews the time-lapse off-axis digital holographic microscopy (DHM) integrated with information processing algorithms for automatically measuring dynamic quantitative phase profiles of beating cardiomyocytes. The off-axis DHM provides time-lapse quantitative phase images (QPI) of cardiomyocytes at 10Hz for one minute. Experimental results show that multiple dynamic parameters of beating cardiomyocytes can be analyzed by the presented automated procedures specifically dedicated to process the time-lapse DHM phase images. The presented method can be useful in quantitative analysis between normal cardiomyocytes beating profile and all other abnormal activities and these multiple beating parameters of cardiomyocytes can be used to characterize the physiological state of cardiomyocytes.

Paper Details

Date Published: 16 May 2018
PDF: 5 pages
Proc. SPIE 10666, Three-Dimensional Imaging, Visualization, and Display 2018, 106660M (16 May 2018); doi: 10.1117/12.2294475
Show Author Affiliations
Inkyu Moon, Daegu Gyeongbuk Institute of Science & Technology (Korea, Republic of)
Keyvan Jaferzadeh, Daegu Gyeongbuk Institute of Science & Technology (Korea, Republic of)


Published in SPIE Proceedings Vol. 10666:
Three-Dimensional Imaging, Visualization, and Display 2018
Bahram Javidi; Jung-Young Son; Osamu Matoba, Editor(s)

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