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Proceedings Paper

Deep 3D convolution neural network for CT brain hemorrhage classification
Author(s): Kamal Jnawali; Mohammad R. Arbabshirani; Navalgund Rao; Alpen A. Patel M.D.
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Paper Abstract

Intracranial hemorrhage is a critical conditional with the high mortality rate that is typically diagnosed based on head computer tomography (CT) images. Deep learning algorithms, in particular, convolution neural networks (CNN), are becoming the methodology of choice in medical image analysis for a variety of applications such as computer-aided diagnosis, and segmentation. In this study, we propose a fully automated deep learning framework which learns to detect brain hemorrhage based on cross sectional CT images. The dataset for this work consists of 40,367 3D head CT studies (over 1.5 million 2D images) acquired retrospectively over a decade from multiple radiology facilities at Geisinger Health System. The proposed algorithm first extracts features using 3D CNN and then detects brain hemorrhage using the logistic function as the last layer of the network. Finally, we created an ensemble of three different 3D CNN architectures to improve the classification accuracy. The area under the curve (AUC) of the receiver operator characteristic (ROC) curve of the ensemble of three architectures was 0.87. Their results are very promising considering the fact that the head CT studies were not controlled for slice thickness, scanner type, study protocol or any other settings. Moreover, the proposed algorithm reliably detected various types of hemorrhage within the skull. This work is one of the first applications of 3D CNN trained on a large dataset of cross sectional medical images for detection of a critical radiological condition

Paper Details

Date Published: 27 February 2018
PDF: 7 pages
Proc. SPIE 10575, Medical Imaging 2018: Computer-Aided Diagnosis, 105751C (27 February 2018); doi: 10.1117/12.2293725
Show Author Affiliations
Kamal Jnawali, Geisinger Health System (United States)
Rochester Institute of Technology (United States)
Mohammad R. Arbabshirani, Geisinger Health System (United States)
Navalgund Rao, Rochester Institute of Technology (United States)
Alpen A. Patel M.D., Geisinger Health System (United States)

Published in SPIE Proceedings Vol. 10575:
Medical Imaging 2018: Computer-Aided Diagnosis
Nicholas Petrick; Kensaku Mori, Editor(s)

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