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Proceedings Paper

Bronchial based pulmonary acinus analysis in human lungs using a synchrotron radiation micro-CT
Author(s): K. Saito; Y. Kobayashi; Y. Kawata; N. Niki; K. Umetani; T. Okamoto; H. Sakai; Y. Nakano; H. Itoh
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Paper Abstract

Quantitative analyses of three-dimensional (3D) micro structures in human lungs can provide detailed information to elucidate pulmonary disease progress. The observation of tissue specimens in two-dimensional (2D) slice of lungs has a limited understanding of the whole of 3D lung peripheral structures. A 3D analysis of the human pulmonary acinus is fundamental to understand lung structure. However, we cannot yet thoroughly understand the 3D lung microstructure because of technical limitations. The lung specimens used in this study were fixed, inflated and dried according to the Heitzman method. Each lung specimen was taken in the beam line BL20B2 at SPring8. The present findings may give further insight in the 3D lung microstructure.

Paper Details

Date Published: 12 March 2018
PDF: 6 pages
Proc. SPIE 10578, Medical Imaging 2018: Biomedical Applications in Molecular, Structural, and Functional Imaging, 105781W (12 March 2018); doi: 10.1117/12.2293428
Show Author Affiliations
K. Saito, Tokushima Univ. (Japan)
Y. Kobayashi, Tokushima Univ. (Japan)
Y. Kawata, Tokushima Univ. (Japan)
N. Niki, Tokushima Univ. (Japan)
K. Umetani, Japan Synchrotron Research Institute (Japan)
T. Okamoto, Cleveland Clinic Heart and Vascular Institute (United States)
H. Sakai, Hyogo Prefectural Amagasaki General Medical Ctr. (Japan)
Y. Nakano, Shiga Univ. of Medical Science (Japan)
H. Itoh, Univ. of Fukui (Japan)

Published in SPIE Proceedings Vol. 10578:
Medical Imaging 2018: Biomedical Applications in Molecular, Structural, and Functional Imaging
Barjor Gimi; Andrzej Krol, Editor(s)

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