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Proceedings Paper

hyperspectral characterization of tissue simulating phantoms using a supercontinuum laser in a spatial frequency domain imaging instrument
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Paper Abstract

Hyperspectral Imaging (HSI) is a growing field in tissue optics due to its ability to collect continuous spectral features of a sample without a contact probe. Spatial Frequency Domain Imaging (SFDI) is a non-contact wide-field spectral imaging technique that is used to quantitatively characterize tissue structure and chromophore concentration. In this study, we designed a Hyperspectral SFDI (H-SFDI) instrument which integrated a supercontinuum laser source to a wavelength tuning optical configuration and a sCMOS camera to extract spatial (Field of View: 2cm×2cm) and broadband spectral features (580nm-950nm). A preliminary experiment was also performed to integrate the hyperspectral projection unit to a compressed single pixel camera and Light Labeling (LiLa) technique.

Paper Details

Date Published: 19 February 2018
PDF: 7 pages
Proc. SPIE 10486, Design and Quality for Biomedical Technologies XI, 104860G (19 February 2018); doi: 10.1117/12.2291369
Show Author Affiliations
Mohammad Torabzadeh, Beckman Laser Institute and Medical Clinic (United States)
Univ. of California, Irvine (United States)
Patrick Stockton, Colorado State Univ. (United States)
Gordon T. Kennedy, Beckman Laser Institute and Medical Clinic (United States)
Rolf B. Saager, Beckman Laser Institute and Medical Clinic (United States)
Anthony J. Durkin, Beckman Laser Institute and Medical Clinic (United States)
Univ. of California, Irvine (United States)
Randy A. Bartels, Colorado State Univ. (United States)
Bruce J. Tromberg, Beckman Laser Institute and Medical Clinic (United States)
Univ. of California, Irvine (United States)


Published in SPIE Proceedings Vol. 10486:
Design and Quality for Biomedical Technologies XI
Ramesh Raghavachari; Rongguang Liang, Editor(s)

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