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Proceedings Paper

Femtosecond laser induced periodic nanostructures formation on medical polymer plate surface for control of cell spreading
Author(s): K. Takenaka; M. Tsukamoto; T. Ooga; Y. Sato; K. Murai; S. Asai
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Paper Abstract

Poly-methyl methacrylate (PMMA) has been widely used as biomaterial. In order to add a new function to PMMA, we developed a method to form periodic nanostructures on PMMA surface by femtosecond laser irradiation with a wavelength of 800 nm. Since PMMA had a low absorbance of light in the near-infrared wavelength region, it was difficult to form the structures by femtosecond laser irradiation on PMMA surface. We proposed a method that the femtosecond laser was focused on a titanium (Ti) plate surface through a polymer plate. As a result, the depth of the periodic nanostructures was about 70 nm, and the period of it was about 410 nm. A cell cultivation test was carried out on PMMA plate with and without periodic nanostructures. Consequently, although cells (MG-63) on the non-irradiated PMMA plate were spread in a random direction, cell spreading on the PMMA plate with periodic nanostructures occurs along the grooves.

Paper Details

Date Published: 16 February 2018
PDF: 6 pages
Proc. SPIE 10519, Laser Applications in Microelectronic and Optoelectronic Manufacturing (LAMOM) XXIII, 105191A (16 February 2018); doi: 10.1117/12.2290224
Show Author Affiliations
K. Takenaka, Osaka Univ. (Japan)
M. Tsukamoto, Osaka Univ. (Japan)
T. Ooga, Osaka Univ. (Japan)
Y. Sato, Osaka Univ. (Japan)
K. Murai, National Institute of Advanced Industrial Science and Technology (Japan)
S. Asai, Osaka Univ. (Japan)

Published in SPIE Proceedings Vol. 10519:
Laser Applications in Microelectronic and Optoelectronic Manufacturing (LAMOM) XXIII
Beat Neuenschwander; Costas P. Grigoropoulos; Tetsuya Makimura; Gediminas Račiukaitis, Editor(s)

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