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Proceedings Paper

A multifunctional endoscope for imaging, fluid delivery and fluid extraction (Conference Presentation)
Author(s): James Stone; Tushar Choudhary; Helen Parker; Bethany Mills; Adam Marshall; Debaditya Choudhury; Michael Tanner; Harry A. Wood; Kerrianne Harrington; Jonathan Knight; Tim A. Birks; Kevin Dhaliwal M.D.; Mark Bradley

Paper Abstract

We present a multifunctional endoscope capable of imaging, fluid delivery and fluid sampling in the alveolar space. The endoscope consists of an imaging fibre bundle fabricated from cost effective OM1 PCVD graded index preforms made for the telecommunications market. These low-cost fibres could potentially make our endoscope disposable after a single use. The performance of our low-cost imaging fibre bundle is shown to be comparable to the current commercial state-of-the-art. The imaging fibre bundle is packaged alongside two channels for the delivery and extraction of fluids. The fluid delivery channels can be used to deliver fluorescent smart probes for the detection of pathogens and to perform a targeted alveolar lavage without the removal of the imaging fibre as is currently standard procedure. Our endoscope is fully biocompatible and with an overall outer diameter of 1.4 mm allowing it to fit into the standard working channel of a bronchoscope. We demonstrate the use of our endoscope in ex-vivo human lungs. We show alveolar tissue and bacterial imaging over two wavelength bands 520 nm – 600 nm and 650 nm – 750 nm both commonly used for bacterial smart probe detection.

Paper Details

Date Published: 14 March 2018
Proc. SPIE 10488, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII, 104880V (14 March 2018);
Show Author Affiliations
James Stone, Univ. of Bath (United Kingdom)
Tushar Choudhary, Heriot Watt Univ. (United Kingdom)
Helen Parker, The Univ. of Edinburgh (United Kingdom)
Bethany Mills, The Univ. of Edinburgh (United Kingdom)
Adam Marshall, University of Edinburgh (United Kingdom)
Debaditya Choudhury, Heriot-Watt Univ. (United Kingdom)
Michael Tanner, Heriot Watt Univ. (United Kingdom)
Harry A. Wood, Univ. of Bath (United Kingdom)
Kerrianne Harrington, Univ. of Bath (United Kingdom)
Jonathan Knight, Univ. of Bath (United Kingdom)
Tim A. Birks, Univ. of Bath (United Kingdom)
Kevin Dhaliwal M.D., The Univ. of Edinburgh (United Kingdom)
Mark Bradley, The Univ. of Edinburgh (United Kingdom)

Published in SPIE Proceedings Vol. 10488:
Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII
Israel Gannot, Editor(s)

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