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Proceedings Paper

Fabrication and characterization of thermo-responsive gold nanorod assemblies
Author(s): Gilbert Bustamante; Katherine Carrizales; Frank DeLuna; Nicolas Large; Jing Yong Ye
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Paper Abstract

Advancements in nanotechnology sensors have aided in the detection of subtle, but significant cellular deviations that may mark certain stages of diseases. Gold nanorods (GNRs) are often studied for this purpose due to their tunable optical properties and ease in surface functionalization. The absorption properties of GNRs are governed by the localized surface plasmon resonance (LSPR), which strongly depends on the GNR’s aspect ratio and on interparticle interactions. By controlling the coupling of nearby rods, a sensor can be created to respond to temperature fluctuations in the local environment. Here, we fabricated thermo-responsive gold nanorod assemblies by conjugating GNRs in end-to-end or side-by-side configurations using Poly(N-isopropyl acrylamide) (PNIPAM). End-to-end assemblies were fabricated through mixture of GNRs and PNIPAM in DI water. GNRs and PNIPAM were combined in DI water and dimethylformamide (DMF) under sonication to achieve side-by-side configuration. The optical absorption of the assemblies was measured by UV-Visible spectroscopy at different temperatures. As the temperature increased, the polymer contracted and initiated plasmon coupling between the GNRs. The optical spectrum experienced a blue- or red-shift for side-by-side or end-to-end configurations, respectively. Spectral tunability reversal was observed when cooled. Experimental results were verified by finite-difference time-domain (FDTD) calculations, which demonstrated spectral shifts under similar parameters. We present methods for fabrication of thermo-responsive gold nanorods for use as a local thermal nanosensor.

Paper Details

Date Published: 23 February 2018
PDF: 10 pages
Proc. SPIE 10507, Colloidal Nanoparticles for Biomedical Applications XIII, 105070B (23 February 2018);
Show Author Affiliations
Gilbert Bustamante, The Univ. of Texas at San Antonio (United States)
Katherine Carrizales, The Univ. of Texas at San Antonio (United States)
Frank DeLuna, The Univ. of Texas at San Antonio (United States)
Nicolas Large, The Univ. of Texas at San Antonio (United States)
Jing Yong Ye, The Univ. of Texas at San Antonio (United States)

Published in SPIE Proceedings Vol. 10507:
Colloidal Nanoparticles for Biomedical Applications XIII
Marek Osiński; Wolfgang J. Parak; Xing-Jie Liang, Editor(s)

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