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Proceedings Paper

Evaluation of oxygen consumption and acoustics of human vocal fold by using near-infrared spectroscopy (Conference Presentation)
Author(s): Han-Yun Cheng; Jung-Chih Chen; Chih-Hsien Liu; Yung-An Tsou; Zih-Jie Lin; Ching-Cheng Chuang

Paper Abstract

Voice disorder such as vocal fatigue is a common and complex multifaceted clinical problem that presents a significant impact on quality of life. Current diagnostic methods of voice assessment devices are only provide indirect information about the status of vocal fold during voice production. In this study, the near-infrared diffuse optical technique (NIRS-DOT) was proposed as a novel approach for human vocal fold oxygen consumption detection and acoustic assessment simultaneously. A total of twenty healthy subjects including ten male and ten female adults of age-matched were recruited with vocal loading task (to trigger a mild inflammation of the vocal fold) for this study. The concentration changes in oxygenated hemoglobin (Δ[HbO2]) and deoxygenated hemoglobin (Δ[Hb]) of vocal fold and voice production with two conditions i.e., pre-vocal loading and after-vocal loading task, are all measured by using NIRS-DOT for functional and acoustic spectrum analysis. In the results of vocal fold oxygen consumption detection, the Δ[Hb] is increased and the Δ[HbO2] is no significant changed after-vocal loading task that may provide useful information on the relationship between oxygen consumption and supply for vocal cord diagnosis. Besides, the acoustic spectrum analysis of voice production is highly correlated with traditional voice assessment devices. Therefore, with the information obtained from this novel approach, the NIRS-DOT can provide not only oxygen consumption analysis but also acoustic spectrum analysis for clinical applications of voice disorder.

Paper Details

Date Published: 14 March 2018
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Proc. SPIE 10469, Optical Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and Otolaryngology 2018, 1046904 (14 March 2018); doi: 10.1117/12.2287704
Show Author Affiliations
Han-Yun Cheng, Institute of Biomedical Engineering, National Chiao Tung Univ. (Taiwan)
Jung-Chih Chen, Institute of Biomedical Engineering, National Chiao Tung Univ. (Taiwan)
Chih-Hsien Liu, Cathay General Hospital (Taiwan)
Yung-An Tsou, China Medical Univ. Hospital (Taiwan)
Zih-Jie Lin, China Medical Univ. Hospital (Taiwan)
Ching-Cheng Chuang, Institute of Biomedical Engineering, National Chiao Tung Univ. (Taiwan)


Published in SPIE Proceedings Vol. 10469:
Optical Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and Otolaryngology 2018
Brian J. F. Wong M.D.; Justus F. Ilgner M.D.; Max J. Witjes M.D., Editor(s)

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