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Proceedings Paper

Influence of low temperature ageing on optical and mechanical properties of transparent yittria stabilized-zirconia cranial prosthesis
Author(s): Nami Davoodzadeh; Gottlieb Uahengo; David Halaney; Javier E. Garay; Guillermo Aguilar
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Paper Abstract

Laser-based diagnostics and therapeutics show promise for many neurological disorders. However, the poor transparency of cranial bone limits the spatial resolution and interaction depth that can be achieved. We addressed this limitation previously, by introducing a novel cranial prosthesis made of a transparent nanocrystalline yttria-stabilized zirconia (nc-YSZ) which aims to enhance the diagnosis and treatment of neurological diseases by providing chronic optical access to the brain. By using optical coherence tomography, we have demonstrated the initial feasibility of ncYSZ implants for cortical imaging in an acute murine model. Although zirconia-based implants have been known for their excellent mechanical properties, the in vivo application was found to be affected by long-term failures, due to low temperature degradation. Accelerated aging simulations in humid environments at slightly elevated temperatures and over long periods typically transforms the ceramic surface into a monoclinic structure through a stress-corrosion-type mechanism. It was expected that the new nc-YSZ would show sufficient resistance to humid environments in comparison to the conventional zirconia implant. However, even a modest amount of transformation can change optical characteristics such as transparency. Herein we present the results of a simulated ageing study following the guidelines from the ISO 13356:2008 on aging of surgical zirconia ceramics. Comparison of %monoclinic transformation, optical transparency and mechanical hardness of nc-YSZ samples at baseline and following 25 and 100 h hydrothermal treatments shows our implant can withstand these extended ageing treatments.

Paper Details

Date Published: 19 February 2018
PDF: 6 pages
Proc. SPIE 10486, Design and Quality for Biomedical Technologies XI, 104860A (19 February 2018);
Show Author Affiliations
Nami Davoodzadeh, Univ. of California, Riverside (United States)
Gottlieb Uahengo, Univ. of California, San Diego (United States)
David Halaney, Univ. of California, Riverside (United States)
Javier E. Garay, Univ. of California, San Diego (United States)
Guillermo Aguilar, Univ. of California, Riverside (United States)

Published in SPIE Proceedings Vol. 10486:
Design and Quality for Biomedical Technologies XI
Ramesh Raghavachari; Rongguang Liang, Editor(s)

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