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Proceedings Paper

Optical mapping of the brain activity in children with Down's syndrome
Author(s): Zhen Yuan; Fengmei Lu
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Paper Abstract

Down’s syndrome (DS) has been shown to be associated with many neurological complications, including cognitive deficits, seizures, early-onset dementia that resembles Alzheimer’s disease, and neurological complications of systemic disorders. DS patients show to have poor performance in executive functions (EF) and fine motor skills. In this study, we examined the brain hemodynamic responses and brain activation patterns of DS children during the completion of EF tasks. Revealing its neural mechanism of DS is not only able to contribute to the early intervention of this children with DS, but also increase understanding of developmental cascades in childhood.

Paper Details

Date Published: 8 February 2018
PDF: 13 pages
Proc. SPIE 10480, Clinical and Translational Neurophotonics 2018, 1048009 (8 February 2018); doi: 10.1117/12.2286795
Show Author Affiliations
Zhen Yuan, Univ. of Macau (Macao, China)
Fengmei Lu, Univ. of Macau (Macao, China)


Published in SPIE Proceedings Vol. 10480:
Clinical and Translational Neurophotonics 2018
Steen J. Madsen; Victor X. D. Yang, Editor(s)

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