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Proceedings Paper

Practical nonlinear method for detection of respiratory and cardiac dysfunction in human subjects
Author(s): Richard A. Katz; Michael S. Lawee; Anthony Kief Newman; J. Woodrow Weiss; Shalabh Chandra; Richard A. Grimm; James D. Thomas
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Paper Abstract

This research applies novel nonlinear signal detection techniques in studies of human subjects with respiratory and cardiac diseases. One of the studies concerns a breathing disorder during sleep, a disease called Obstructive Sleep Apnea (OSA). In a second study we investigate a disease of the heart, Atrial Fibrillation (AF). The former study involves nonlinear processing of the time sequences of sleep apnea recordings (cardio-respirograms) collected from patients with known obstructive sleep apnea, and from a normal control. In the latter study, we apply similar nonlinear metrics to Doppler flow measurements obtained by transesophageal echocardiography (TEE). One of our metrics, the 'chaotic radius' is used for tracking the position of points in phase space relative to some reference position. A second metric, the 'differential radius' provides a measure of the separation rate of contiguous (evolving) points in phase space. A third metric, the 'chaotic frequency' gives angular position of the phase space orbit as a function of time. All are useful for identifying change of physiologic condition that is not always apparent using conventional methods.

Paper Details

Date Published: 1 December 1995
PDF: 18 pages
Proc. SPIE 2612, Chaotic Circuits for Communication, (1 December 1995); doi: 10.1117/12.227899
Show Author Affiliations
Richard A. Katz, Naval Underseas Warfare Ctr. (United States)
Michael S. Lawee, Winmar Diagnostics (United States)
Anthony Kief Newman, Winmar Diagnostics (United States)
J. Woodrow Weiss, Harvard Medical School (United States)
Shalabh Chandra, Cleveland Clinic Foundation (United States)
Richard A. Grimm, Cleveland Clinic Foundation (United States)
James D. Thomas, Cleveland Clinic Foundation (United States)

Published in SPIE Proceedings Vol. 2612:
Chaotic Circuits for Communication
Jaafar M. H. Elmirghani, Editor(s)

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