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Proceedings Paper

Phase retrieval for crystalline specimens
Author(s): Romain A. Arnal; Rick P. Millane
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Paper Abstract

The recent availability of ultra-bright and ultra-short X-rays pulses from new sources called x-ray free-electron lasers (XFELs) has introduced a new paradigm in X-ray crystallography. Called "diffraction-before-destruction," this paradigm addresses the main problems that plague crystallography using synchrotron sources. However, the phase problem of coherent diffraction imaging remains: one has to retrieve the phase of the measured diffraction amplitude in order to reconstruct the object. Fibrous and membrane proteins that crystallize in 1D and 2D crystals can now potentially be used for data collection with free-electron lasers. The crystallographic phase problem with such crystalline specimens is eased as the Fourier amplitude can be sampled more finely than at the Bragg sampling along one or two directions. Here we characterise uniqueness of the phase problem for different types of crystalline specimen. Simulated ab initio phase retrieval using iterative projection algorithms for 2D crystals is presented.

Paper Details

Date Published: 6 September 2017
PDF: 7 pages
Proc. SPIE 10410, Unconventional and Indirect Imaging, Image Reconstruction, and Wavefront Sensing 2017, 104100N (6 September 2017); doi: 10.1117/12.2275411
Show Author Affiliations
Romain A. Arnal, Univ. of Canterbury (New Zealand)
Rick P. Millane, Univ. of Canterbury (New Zealand)

Published in SPIE Proceedings Vol. 10410:
Unconventional and Indirect Imaging, Image Reconstruction, and Wavefront Sensing 2017
Jean J. Dolne; Rick P. Millane, Editor(s)

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