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Proceedings Paper

Laser speckle contrast imaging augmented with structured light
Author(s): Jaime Necochea; Jaime Prieto; Zachary Hoffman; Charles DiMarzio
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Paper Abstract

This paper presents a new method of blood flow imaging in vessels within and underneath the skin. The combination of Laser Speckle Contrast Imaging (LSCI) and Spatial Frequency Domain Imaging (SFDI)/ Structured Illumination Microscopy (SIM) allows one to retrieve a substantial amount of flow information, which is otherwise occluded by the skin. In this article, the experiment consists of illuminating a phantom with coherent light passing through a grid pattern which is modulated at the plane of interest. The speckle pattern is then imaged and processed using a combination of structured illumination sectioning and laser speckle contrast. The whole process is realized using an inexpensive setup consisting of a laser diode (Wavelength = 758 nm), mirrors, lenses, a grid and an 8-bit camera. This advanced, yet easy to implement, technique will allow deep skin imaging to be fast, effective and inexpensive.

Paper Details

Date Published: 24 February 2017
PDF: 11 pages
Proc. SPIE 10070, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXIV, 100701F (24 February 2017); doi: 10.1117/12.2275272
Show Author Affiliations
Jaime Necochea, Northeastern Univ. (United States)
Jaime Prieto, Northeastern Univ. (United States)
Zachary Hoffman, Northeastern Univ. (United States)
Charles DiMarzio, Northeastern Univ. (United States)

Published in SPIE Proceedings Vol. 10070:
Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXIV
Thomas G. Brown; Carol J. Cogswell; Tony Wilson, Editor(s)

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