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Proceedings Paper

Probing the dynamics of spontaneous cortical activities via widefield Ca+2 imaging in GCaMP6 transgenic mice
Author(s): Li Zhu; Christian R. Lee; David J. Margolis; Laleh Najafizadeh
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Paper Abstract

Studying the temporal and spectral characteristics of brain function under spontaneous activity has been recently receiving great interest in the field of neuroscience. By combining wavelet coherence and multivariate permutation test, this paper presents a new method for investigating changes in functional connectivity under spontaneous activity. The proposed method does not impose any prior assumption about the frequency bands that are involved in the activity, nor on the distribution of the data. The proposed method is applied on data obtained from widefield transcranial calcium imaging of GCaMP6 transgenic mice. Results on how function connectivity corresponding to two forms of spontaneous activity differ across frequency and space are presented.

Paper Details

Date Published: 21 November 2017
PDF: 8 pages
Proc. SPIE 10394, Wavelets and Sparsity XVII, 103940C (21 November 2017); doi: 10.1117/12.2274119
Show Author Affiliations
Li Zhu, Rutgers, The State Univ. of New Jersey (United States)
Christian R. Lee, Rutgers, The State Univ. of New Jersey (United States)
David J. Margolis, Rutgers, The State Univ. of New Jersey (United States)
Laleh Najafizadeh, Rutgers, The State Univ. of New Jersey (United States)


Published in SPIE Proceedings Vol. 10394:
Wavelets and Sparsity XVII
Yue M. Lu; Dimitri Van De Ville; Manos Papadakis, Editor(s)

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