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Proceedings Paper

Finite element model for the simulation of laser activated micro- and nano-scale drug delivery systems
Author(s): Henrique Vilhena; João M. P. Coelho; José M. Rebordão
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Paper Abstract

This paper describes a flexible model that can be used to simulate laser-based photoactivation of drug delivery systems. It considers Gaussian beams for the excitation while the heat diffusion equation is solved by use of the finite element method. As an example, a typical liposome geometry in the focal volume of a laser beam is simulated and the results are compared with experimental data obtained in the literature, showing a good agreement. The model has potential in the design of drug delivery systems as it can be a starting point for the development of new kinds of micro- and nano-scale drug delivery systems.

Paper Details

Date Published: 22 August 2017
PDF: 6 pages
Proc. SPIE 10453, Third International Conference on Applications of Optics and Photonics, 104531Y (22 August 2017); doi: 10.1117/12.2272721
Show Author Affiliations
Henrique Vilhena, Glasgow Caledonian Univ. (United Kingdom)
João M. P. Coelho, Univ. de Lisboa (Portugal)
José M. Rebordão, Univ. de Lisboa (Portugal)

Published in SPIE Proceedings Vol. 10453:
Third International Conference on Applications of Optics and Photonics
Manuel Filipe P. C. M. Martins Costa, Editor(s)

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