Share Email Print

Proceedings Paper

Multi-modal spectroscopic imaging with synchrotron light to study mechanisms of brain disease
Author(s): Kelly L. Summers; Nicholas Fimognari; Ashley Hollings; Mitchell Kiernan; Virginie Lam; Rebecca J. Tidy; Ryu Takechi; Graham N. George; Ingrid J. Pickering; John C. Mamo; Hugh H. Harris; Mark J. Hackett
Format Member Price Non-Member Price
PDF $17.00 $21.00

Paper Abstract

The international health care costs associated with Alzheimer’s disease (AD) and dementia have been predicted to reach $2 trillion USD by 2030. As such, there is urgent need to develop new treatments and diagnostic methods to stem an international health crisis. A major limitation to therapy and diagnostic development is the lack of complete understanding about the disease mechanisms. Spectroscopic methods at synchrotron light sources, such as FTIR, XRF, and XAS, offer a “multi-modal imaging platform” to reveal a wealth of important biochemical information in situ within ex vivo tissue sections, to increase our understanding of disease mechanisms.

Paper Details

Date Published: 29 April 2017
PDF: 1 pages
Proc. SPIE 10340, International Conference on Biophotonics V, 1034002 (29 April 2017); doi: 10.1117/12.2272365
Show Author Affiliations
Kelly L. Summers, Curtin Univ. (Australia)
Nicholas Fimognari, Curtin Univ. (Australia)
Ashley Hollings, Curtin Univ. (Australia)
Mitchell Kiernan, Curtin Univ. (Australia)
Virginie Lam, Curtin Univ. (Australia)
Rebecca J. Tidy, Curtin Univ. (Australia)
Ryu Takechi, Curtin Univ. (Australia)
Graham N. George, Curtin Univ. (Australia)
Ingrid J. Pickering, Curtin Univ. (Australia)
John C. Mamo, Curtin Univ. (Australia)
Hugh H. Harris, Curtin Univ. (Australia)
Mark J. Hackett, Curtin Univ. (Australia)

Published in SPIE Proceedings Vol. 10340:
International Conference on Biophotonics V
David D. Sampson; Dennis L. Matthews; Jürgen Popp; Halina Rubinsztein-Dunlop; Brian C. Wilson, Editor(s)

© SPIE. Terms of Use
Back to Top
Sign in to read the full article
Create a free SPIE account to get access to
premium articles and original research
Forgot your username?