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Proceedings Paper

Mueller matrix imaging and analysis of cancerous cells
Author(s): A. Fernández; J. L. Fernández-Luna; F. Moreno; J. M. Saiz
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Paper Abstract

Imaging polarimetry is a focus of increasing interest in diagnostic medicine because of its non-invasive nature and its potential for recognizing abnormal tissues. However, handling polarimetric images is not an easy task, and different intermediate steps have been proposed to introduce physical parameters that may be helpful to interpret results. In this work, transmission Mueller matrices (MM) corresponding to cancer cell samples have been experimentally obtained, and three different transformations have been applied: MM-Polar Decomposition, MM-Transformation and MM-Differential Decomposition. Special attention has been paid to diattenuation as a sensitive parameter to identify apoptosis processes induced by cisplatin and etoposide.

Paper Details

Date Published: 22 August 2017
PDF: 7 pages
Proc. SPIE 10453, Third International Conference on Applications of Optics and Photonics, 104531J (22 August 2017); doi: 10.1117/12.2272141
Show Author Affiliations
A. Fernández, Univ. de Cantabria (Spain)
J. L. Fernández-Luna, Hospital Univ. Marqués de Valdecilla (Spain)
F. Moreno, Univ. de Cantabria (Spain)
J. M. Saiz, Univ. de Cantabria (Spain)

Published in SPIE Proceedings Vol. 10453:
Third International Conference on Applications of Optics and Photonics
Manuel Filipe P. C. M. Martins Costa, Editor(s)

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