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Proceedings Paper

Laser based manufacturing of channels and improvement of their lifetime with sol-gel coatings
Author(s): María Aymerich; Ana I. Gómez-Varela; Ezequiel Álvarez; M. Teresa Flores-Arias
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Paper Abstract

A preclinical device that mimics half blood vessel by using laser technologies has been developed. By employing a Nd:YVO4 laser a channel has been manufactured over soda-lime glass. Using a CO2 laser combined with a roller furnace, a thermal treatment has been applied to the channel to enhance its quality. The glass structure was employed as master to replicate the channel in PDMS by soft-lithography. To avoid the deterioration of the PDMS, channels were coated with three different sol-gel coatings compositions. Endothelial cells were cultured over the channels to determine the most suitable surface for cell growing.

Paper Details

Date Published: 22 August 2017
PDF: 5 pages
Proc. SPIE 10453, Third International Conference on Applications of Optics and Photonics, 104530N (22 August 2017); doi: 10.1117/12.2271778
Show Author Affiliations
María Aymerich, Univ. de Santiago de Compostela (Spain)
Ana I. Gómez-Varela, Univ. de Santiago de Compostela (Spain)
Ezequiel Álvarez, Instituto de Investigación Sanitaria de Santiago de Compostela (Spain)
M. Teresa Flores-Arias, Univ. de Santiago de Compostela (Spain)

Published in SPIE Proceedings Vol. 10453:
Third International Conference on Applications of Optics and Photonics
Manuel Filipe P. C. M. Martins Costa, Editor(s)

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