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Proceedings Paper

Development and analytical performance evaluation of FREND-SAA and FREND-Hp
Author(s): Eunha Choi; Jihyun Seong; Seiyoung Lee; Changseop Lee; Sunmi Han
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Paper Abstract

The FREND System is a portable cartridge reader, quantifying analytes by measuring laser-induced fluorescence in a single-use reagent cartridge. The objective of this study was to evaluate FREND-SAA and FREND-Hp assays. The FREND-SAA and Hp assays were standardized to the WHO and IFCC reference materials. Analytical performance studies of Precision, Linearity, Limits of Detections, Interferences, and Method Comparisons for both assays were performed according to the CLSI guidelines. Both assays demonstrated acceptable imprecision of %CV in three different levels of samples. The linearity of the assays was found to be acceptable (SAA 5~150 mg/L, Hp 30~400 mg/dL). The detection limits were 3.8 mg/L (SAA) and 10.2 mg/dL (Hp). No significant interference and no significant deviation from linearity was found in the both comparison studies. In conclusion, NanoEnTek’s FREND-SAA and Hp assays represent rapid, accurate and convenient means to quantify SAA and Hp in human serum on FREND system.

Paper Details

Date Published: 12 July 2017
PDF: 5 pages
Proc. SPIE 10324, International Conference on Nano-Bio Sensing, Imaging, and Spectroscopy 2017, 103240A (12 July 2017); doi: 10.1117/12.2270649
Show Author Affiliations
Eunha Choi, NanoEnTek, Inc. (Korea, Republic of)
Jihyun Seong, NanoEnTek, Inc. (Korea, Republic of)
Seiyoung Lee, NanoEnTek Inc. (Korea, Republic of)
Changseop Lee, NanoEnTek Inc (Korea, Republic of)
Sunmi Han, NanoEnTek, Inc. (Korea, Republic of)

Published in SPIE Proceedings Vol. 10324:
International Conference on Nano-Bio Sensing, Imaging, and Spectroscopy 2017
Jaebum Choo; Seung-Han Park, Editor(s)

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