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Proceedings Paper

Towards non-invasive high-resolution 3D nano-tomography by ultrasonic scanning probe microscopy
Author(s): Hossein J. Sharahi; Gajendra Shekhawat; Vinayak Dravid; Philip Egberts; Seonghwan Kim
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Paper Abstract

Nanoscale imaging techniques that can be used to visualize and characterize local aggregations of the embedded nanoparticulates with sufficient resolution have attracted a great deal of interest. Ultrasonic scanning probe microscopy (SPM) and its derivatives are nondestructive techniques that can be used to elucidate subsurface nanoscale features and mechanical properties. Although many different ultrasonic methods have been used for subsurface imaging, the mechanisms and crucial parameters associated with the contrast formation in subsurface imaging are still unclear. Here, the impact of mechanical properties of the nanoparticulates/matrix, size of the nanoparticulates, buried depth of the nanoparticulates, and the ultrasonic excitation frequency on the developed ultrasonic SPM images have been investigated. To verify our theoretical model, experimental measurements of scanning near-field ultrasound holography (SNFUH) have been recreated in our theoretical analysis to reveal comparable variations in phase contrast measured in SNFUH while scanning over the nanoparticulates embedded in bacteria.

Paper Details

Date Published: 12 July 2017
PDF: 6 pages
Proc. SPIE 10324, International Conference on Nano-Bio Sensing, Imaging, and Spectroscopy 2017, 1032408 (12 July 2017); doi: 10.1117/12.2269817
Show Author Affiliations
Hossein J. Sharahi, Univ. of Calgary (Canada)
Gajendra Shekhawat, Northwestern Univ. (United States)
Vinayak Dravid, Northwestern Univ. (United States)
Philip Egberts, Univ. of Calgary (Canada)
Seonghwan Kim, Univ. of Calgary (Canada)

Published in SPIE Proceedings Vol. 10324:
International Conference on Nano-Bio Sensing, Imaging, and Spectroscopy 2017
Jaebum Choo; Seung-Han Park, Editor(s)

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