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Proceedings Paper

Noninvasive imaging of oral mucosae with optical coherence tomography
Author(s): Cheng-Yu Lee; Wei-Chuan Chen; Meng-Tsan Tsai
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Paper Abstract

In this study, a swept-source optical coherence tomography (OCT) system is developed for in vivo visualization of structural and vascular morphology oral mucosa. For simplification of optical probe fabrication, probe weight, and system setup, the body of the scanning probe is fabricated by a 3D printer to fix the optical components and the mechanical scanning device, and a partially reflective slide is attached at the output end of probe to achieve a common-path configuration. Aside from providing the ability of 3D structural imaging with the developed system, 3D vascular images of oral mucosa can be simultaneously obtained. Then, different locations of oral mucosa are scanned with common-path OCT. The results show that epithelium and lamina propria layers as well as fungiform papilla can be identified and microvascular images can be acquired. With the proposed probe, the system cost and volume can be greatly reduced. Experimental results indicate that such common-path OCT system could be further implemented for oral cancer diagnosis.

Paper Details

Date Published: 18 April 2017
PDF: 3 pages
Proc. SPIE 10251, Biomedical Imaging and Sensing Conference, 102511E (18 April 2017); doi: 10.1117/12.2269384
Show Author Affiliations
Cheng-Yu Lee, Chang Gung Univ. (Taiwan)
Wei-Chuan Chen, Chang Gung Univ. (Taiwan)
Meng-Tsan Tsai, Chang Gung Univ. (Taiwan)
Chang Gung Memorial Hospital (Taiwan)

Published in SPIE Proceedings Vol. 10251:
Biomedical Imaging and Sensing Conference
Toyohiko Yatagai; Yoshihisa Aizu; Osamu Matoba; Yasuhiro Awatsuji, Editor(s)

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