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Proceedings Paper

Contact lens assisted imaging with integrated flexible handheld probe for glaucoma diagnosis
Author(s): Xun Jie Jeesmond Hong; Shinoj V. K.; V. M. Murukeshan; M. Baskaran; Tin Aung
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Paper Abstract

Angle closure glaucoma accounts for majority of the bilateral blindness in Asian countries such as Singapore, China, and India. Abnormalities in the optic nerve and aqueous outflow system are the most indicative clinical hallmarks for glaucoma of this clinical subtype. Traditional photographic imaging techniques to assess the drainage angle are contact based, and may expose patients to risk of corneal abrasion and infections. In addition, these procedures require the use of viscous ophthalmic gels as coupling medium to overcome the phenomenon of total internal reflection at the tear-air interface. In this paper, we propose an integrated flexible handheld probe consisting of a micro color CCD video camera and white light LEDs. The handheld probe is able to capture images of the fundus and opposite iridocorneal angle when placed at the central cornea or limbus respectively. Here, we propose the use of hydrogel contact lens as an index matching medium and better protective barrier, as an alternative to conventional ophthalmic gels. The proposed imaging system and methodology has been successfully tested on porcine eye samples, ex vivo. With its high repeatability, reproducibility, and a good safety profile, it is believed that the proposed imaging system and methodology will complement existing imaging modalities in the diagnosis and management of glaucoma.

Paper Details

Date Published: 13 June 2017
PDF: 6 pages
Proc. SPIE 10449, Fifth International Conference on Optical and Photonics Engineering, 1044908 (13 June 2017); doi: 10.1117/12.2268984
Show Author Affiliations
Xun Jie Jeesmond Hong, Nanyang Technological Univ. (Singapore)
Shinoj V. K., Nanyang Technological Univ. (Singapore)
V. M. Murukeshan, Nanyang Technological Univ. (Singapore)
M. Baskaran, Singapore Eye Research Institute (Singapore)
Singapore National Eye Ctr. (Singapore)
Duke-NUS Medicine School (Singapore)
Tin Aung, Singapore Eye Research Institute (Singapore)
Singapore National Eye Ctr. (Singapore)
Duke-NUS Medicine School (Singapore)

Published in SPIE Proceedings Vol. 10449:
Fifth International Conference on Optical and Photonics Engineering
Anand Krishna Asundi, Editor(s)

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