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Proceedings Paper

Microcirculation monitoring with real time spatial frequency domain imaging
Author(s): Xinlin Chen; Zili Cao; Weihao Lin; Danfeng Zhu; Xiuwei Zhu; Bixin Zeng; M. Xu
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Paper Abstract

We present a spatial frequency domain imaging (SFDI) study of local hemodynamics in the forearm of healthy volunteers performing paced breathing. Real time Single Snapshot Multiple Frequency Demodulation - Spatial Frequency Domain Imaging (SSMD-SFDI) was used to map the optical properties of the subsurface of the forearm continuously. The oscillations of the concentrations of deoxy- and oxyhemoglobin at the subsurface of the forearm induced by paced breathing are found to be close to out-of-phase, attributed to the dominance of the blood flow modulation by paced breathing. The properties of local microcirculation including the blood transit times through capillaries and venules are extracted by fitting to Simplified Hemodynamics Model. Our preliminary results suggest that the real time SSMD-SFDI platform may serve as one effective imaging modality for microcirculation monitoring.

Paper Details

Date Published: 5 January 2017
PDF: 6 pages
Proc. SPIE 10245, International Conference on Innovative Optical Health Science, 102450J (5 January 2017); doi: 10.1117/12.2268805
Show Author Affiliations
Xinlin Chen, Wenzhou Medical Univ. (China)
Zili Cao, Wenzhou Medical Univ. (China)
Weihao Lin, Wenzhou Medical Univ. (China)
Danfeng Zhu, Wenzhou Medical Univ. (China)
Xiuwei Zhu, Wenzhou Medical Univ. (China)
Bixin Zeng, Wenzhou Medical Univ. (China)
M. Xu, Fairfield Univ. (United States)

Published in SPIE Proceedings Vol. 10245:
International Conference on Innovative Optical Health Science
Xingde Li; Qingming Luo, Editor(s)

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