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Proceedings Paper

Study of targeted-treatment on colon cancer cell via spectroscopic imaging ellipsometry
Author(s): Yu-Da Chen; Hao Yun Hsu; Mai Ibrahim Khaleel; Ching-Hsiang Chan; Yia-Chung Chang; Chien-Hsun Wu; Han-Chung Wu
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Paper Abstract

We present the enhancement of targeted treatment on colon cancer cell via microscopic imaging ellipsometry (MIE). All spectroscopic MIE signals on 5μm×5μm area in visible range are captured within the modified Optrel MULTISKOP system. Colon cancer cells are cultured in Bottom-up Millicell EZ SLIDE 4-well structure under the environment (37°C, 10% CO2). Original single colon cancer cell, single colon cancer cell under untargeted-treatment, and single colon cancer cell under targeted-treatment are studied by specular-reflective mode and off-specular scattering mode in this experiment. Some polarization-related and phase-related MIE images are analyzed to reveal the improvement of targeted-treatment by observing changes in specular and off-specular reflectance and absorption.

Paper Details

Date Published: 18 April 2017
PDF: 3 pages
Proc. SPIE 10251, Biomedical Imaging and Sensing Conference, 102511L (18 April 2017); doi: 10.1117/12.2267971
Show Author Affiliations
Yu-Da Chen, National Tsing Hua Univ. (Taiwan)
Academia Sinica (Taiwan)
Hao Yun Hsu, Academia Sinica (Taiwan)
National Taiwan Univ. (Taiwan)
Mai Ibrahim Khaleel, National Tsing Hua Univ. (Taiwan)
Academia Sinica (Taiwan)
Ching-Hsiang Chan, Academia Sinica (Taiwan)
Yia-Chung Chang, Academia Sinica (Taiwan)
National Cheng Kung Univ. (Taiwan)
Chien-Hsun Wu, Academia Sinica (Taiwan)
Han-Chung Wu, Academia Sinica (Taiwan)

Published in SPIE Proceedings Vol. 10251:
Biomedical Imaging and Sensing Conference
Toyohiko Yatagai; Yoshihisa Aizu; Osamu Matoba; Yasuhiro Awatsuji, Editor(s)

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