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Proceedings Paper

Spectroscopic properties of second generation photosensitizers for photo-diagnostics and photo-dynamic therapy
Author(s): Magdalena Ligia Naurecka; Bartosz Michał Sierakowski; Mirosław Kwaśny
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Paper Abstract

The aim of the study was to investigate and compare photophysical properties of the most modern formulations used in the world – derivatives of: porphyrin, chlorines, bacteriochlorins, phthalocyanines and phenothiazines. Useful parameters of comparing the emission properties of various sensitizers groups are quantum yield of singlet oxygen generation (ΦT) and quantum yields of fluorescence (ΦF). The emission and excitation characteristics were appointed and shown as excitation – emission matrices (EX – EM). The influence of the monomerization degree of the pure hematoporphyrin (HP) on the quantum yield was also measured. Received quantum yield values of commonly used sensitizers are in the range 0.05 – 0.3 and efficiency values of singlet oxygen generation are 0.3 – 0.7. These values depend not only on the chemical structure of the compounds, but also on solvent polarity, temperature and concentration which is decisive for the monomerization degree.

Paper Details

Date Published: 8 December 2016
PDF: 12 pages
Proc. SPIE 10159, Laser Technology 2016: Progress and Applications of Lasers, 101590B (8 December 2016); doi: 10.1117/12.2261946
Show Author Affiliations
Magdalena Ligia Naurecka, Military Univ. of Technology (Poland)
Bartosz Michał Sierakowski, Military Univ. of Technology (Poland)
Mirosław Kwaśny, Military Univ. of Technology (Poland)

Published in SPIE Proceedings Vol. 10159:
Laser Technology 2016: Progress and Applications of Lasers
Ryszard S. Romaniuk; Krzysztof Kopczynski; Jan K. Jabczyński; Zygmunt Mierczyk, Editor(s)

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