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Proceedings Paper

Dual-frequency transducer with a wideband PVDF receiver for contrast-enhanced, adjustable harmonic imaging
Author(s): Jinwook Kim; Brooks D. Lindsey; Sibo Li; Paul A. Dayton; Xiaoning Jiang
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Paper Abstract

Acoustic angiography is a contrast-enhanced, superharmonic microvascular imaging method. It has shown the capability of high-resolution and high-contrast-to-tissue-ratio (CTR) imaging for vascular structure near tumor. Dual-frequency ultrasound transducers and arrays are usually used for this new imaging technique. Stacked-type dual-frequency transducers have been developed for this vascular imaging method by exciting injected microbubble contrast agent (MCA) in the vessels with low-frequency (1-5 MHz), moderate power ultrasound burst waves and receiving the superharmonic responses from MCA by a high-frequency receiver (>10 MHz). The main challenge of the conventional dual-frequency transducers is a limited penetration depth (<25 mm) due to the insufficient receiving sensitivity for highfrequency harmonic signal detection. A receiver with a high receiving sensitivity spanning a wide superharmonic frequency range (3rd to 6th) enables selectable bubble harmonic detection considering the required penetration depth. Here, we develop a new dual-frequency transducer composed of a 2 MHz 1-3 composite transmitter and a polyvinylidene fluoride (PVDF) receiver with a receiving frequency range of 4-12 MHz for adjustable harmonic imaging. The developed transducer was tested for harmonic responses from a microbubble-injected vessel-mimicking tube positioned 45 mm away. Despite the long imaging distance (45 mm), the prototype transducer detected clear harmonic response with the contrast-to-noise ratio of 6-20 dB and the -6 dB axial resolution of 200-350 μm for imaging a 200 um-diameter cellulose tube filled with microbubbles.

Paper Details

Date Published: 5 April 2017
PDF: 8 pages
Proc. SPIE 10170, Health Monitoring of Structural and Biological Systems 2017, 101700T (5 April 2017); doi: 10.1117/12.2258571
Show Author Affiliations
Jinwook Kim, North Carolina State Univ. (United States)
Brooks D. Lindsey, The Univ. of North Carolina at Chapel Hill (United States)
North Carolina State Univ. (United States)
Sibo Li, North Carolina State Univ. (United States)
Paul A. Dayton, The Univ. of North Carolina at Chapel Hill (United States)
North Carolina State Univ. (United States)
Xiaoning Jiang, North Carolina State Univ. (United States)

Published in SPIE Proceedings Vol. 10170:
Health Monitoring of Structural and Biological Systems 2017
Tribikram Kundu, Editor(s)

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